Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

2016年,高管薪酬均值达709万元,同比增长8%,跑赢了我国国内生产总值6.7%和人均可支配收入6.3%的增速。
adj. 群众的,大规模
"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."
他表示那个时候的人有另外一种浪漫,人们没有电脑,所以交流都是通过信件,这样其实更浪漫。
本田公司希望NSX将再度彰显其技术致胜的美誉,也希望NSX能提升本田作为高端汽车和卡车制造商的品牌形象。去年美国汽车市场销售增长5.9%,但本田在美销量仅微增1%——这意味着该公司失去了一部分市场份额,最重要的是,本田在与其两大主要对手丰田和日产的角逐中落于下风。
May the season\'s joy fill you all the year round.
The report provided in-depth observations on 28 Chinese business and administrative capitals - excluding Beijing and Shanghai - using several indicators.
Here are our top 10expectations for China in 2014:
May your New Year be filled with special moment, warmth, peace and happiness, the joy of covered ones near, and wishing you all the joys of Christmas and a year of happiness.愿你的新年充满温馨,祥和,与亲人团聚的快乐,祝乐陶陶,新年乐无限。
Recent years have seen a return of the bacterial infection, reaching numbers not seen since the 1960s, with admissions for a primary diagnosis more than doubling between 2010/11 and 2017/18, from 429 to more than 1,300.
谷歌的品牌价值现在超过了1090亿美元,比苹果公司要高大约20亿美元,这使其成为了全世界最赚钱的公司。
现年60岁的罗斯是位于波士顿的哈佛大学的教授,而89岁的沙普利是美国加州大学洛杉矶分校的教授。
学会控制自己的情绪,控制自己的想法,克服对被拒绝的恐惧,学会向别人敞开心扉。
More than 350,000 gamers from across Europe (and some from North America and Asia) have made the annual pilgrimage to the quaint German city of Cologne, which has a population of just over 1 million. Activision used the convention to debut its multiplayer gameplay for Sledgehammer Games’ Call of Duty: Advanced Warfare, allowing attendees hands-on access to the November 3 release.
中国投资10亿美金用以将进一步打造C9大学(中国最好的9所大学)。 经费将会主要用来吸引顶级的教职人员,建造世界一流的教学设施,和招募一流的声源。中国将会国际智力、教育和技能的人才大战中逐鹿。
威尼斯位于意大利东北部,约建成于公元5世纪,由118个小岛组成,凭借其迷人的水上景观、多样的建筑风格和琳琅满目的艺术品而闻名于世。
Theresa May is still facing resistance from within her own party. Vince Cable, the Liberal Democrats’ sage and leader, still thinks Brexit may not really happen.
安联:小奥运会
他们开始对无保障合同、不稳定的工作时间安排、微薄的工资以及依托优步(Uber)等在线零工经济平台的新形态工作感到忧心忡忡。总部位于巴黎的有影响力的富国俱乐部——经济合作与发展组织(OECD)将于2018年发布《就业战略》,其中可能会更加强调工作的质量和包容性。
继Facebook前员工肖恩帕克(Sean Parker)和查马斯帕里哈皮蒂亚(Chamath Palihapitiya)——二人谴责了社交媒体的成瘾性——之后,新的一年将有更多的科技行业工作者发声。
Renters
The average pay for executives in educational companies was the lowest, just over 2.8 million yuan and about one tenth that of their counterparts in the financial sector.
The Global Obesity Epidemic
A median forecast from economists had predicted a 0.9 per cent rise.
对于俄罗斯这一前苏联(解体于1991年)的15个继任国之一,在2015年还能否稳坐世界大国的宝座,仍有讨论的余地。


Global smartphone shipments reached 1.47 billion units in 2016, up by 2.3 percent from last year, said IDC.
There are no right or wrong answers, just be honest with yourself.
Notable newcomers to the list include Cameron Mackintosh, the first theater producer to enter the ranks, WeWork's Adam Neumann and Miguel McKelvey and Pinterest's Ben Silbermann and Evan Sharp.


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

A sub-index tracking activity at larger enterprises softened 0.7 points to 53.1, while mid-sized companies fell 1.3 points to 49.9, indicating slight contraction. That for smaller manufacturers fell 0.4 points to 49, indicating worsening contraction.
HSBC said its private reading of China's manufacturing sector was stagnant last month, confirming a "flash" estimate already published.
再来看一下流失顾客的公司吧。
The estimates include earnings from movies, TV and endorsements from cosmetic and other companies. Bollywood star Deepika Padukone is the only newcomer on the list.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

这个家庭中心内部有三个摄像头,它能够连接到你的手机,你可以通过手机看冰箱里有什么。所以它基本上是一个6000美元替代用纸笔完成购物清单的替代品。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

It is the thirdhighest overall behind the two Indian management academies at Ahmedabad and Bangalore, with respective salaries of $109,000 and $106,000.
But now she's using her storybook looks for good, dressing up as the character to entertain children and cheer-up cancer patients.

迄今为止,Bigcommerce同名技术的吸引力就在于其简单性,以及与商户同步成长的能力。史蒂夫o凯斯说,“对于一些人来说,成败即系于此。”凯斯以公司董事的身份为Bigcommerce提供美国创业趋势方面的建议。“就在五年前,如果要打造一家有吸引力的网店,你需要花费几十万美元。如今,几个小时就可以搞定,每月成本还不到100美元。”
Twenty years of global negotiations aimed at slowing the growth of heat-trapping emissions have yielded little progress. However, 2014 saw signs of large-scale political mobilization on the issue, as more than 300,000 people marched in New York City in September, and tens of thousands more took to the streets in other cities around the world.
会。目前有很多利好因素:利润、经济增长和美国减税。但这些都是已知因素。按照历史标准看,眼下股价高得离谱,但这对短期走势毫无参考价值。最终还是要看流动性,自从股市在2009年从危机中走出来以后,流动性始终驱动着股市上涨。如果一切按计划进行,到2018年底,各国央行会在缩表和撤除流动性。如果各央行果真这样做,标普500指数很可能会牛气不再。但只要稍有风吹草动,央行官员们就会迟疑。这股牛气应该会继续。
紧随其后的是亚马逊创始人杰夫·贝索斯,这是他第一次排名第三,由于亚马逊股值飙升,他的资产达到了728亿美元。
Recipient: Their Royal Highnesses The Duke and Duchess of Cambridge (joint winners)
“邦德对待女人的态度是那种高高在上的、肉欲的,这完全符合007系列小说中邦德的形象。但我创作出十分强势的女人,与他难分伯仲地竞争,他的看法由此受到挑战。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


两大家居电商抢滩成都 四川家具圈硝烟弥漫


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


具体来说,广电总局表示,2016年中国票房总额达到457亿元人民币(约66亿美元),比2015年增长3.7%。
2.Hold themselves and others accountable
IT/通信/电子/互联网行业的应届生签约最高月薪为4867元,同比去年下降826元;紧随其后的是金融业和交通/运输/物流/仓储行业,平均签约月薪分别是4692元和4457元。
报告提供了对除北京和上海之外的28个国内商业和行政中心城市进行的深入考察。
数据还显示,网红的分布和经济发展水平也有密切关系,北京、上海、广东、江苏和浙江等较发达地区是网红分布最多的五个地区。
如果将其切成八片,每片的价值就是250美元,相当于每一口大约值50美元。
“…was caught in a big lie on her resume during the meeting.”
现在iPhone又夺回声势,对Apple Watch的期待也在升温,库克似乎重新赢得了苹果员工的信任。分析师表示,这一点从他在今年产品发布会上的表现就可以看出来。
Given that Dallas resisted tanking for years as Dirk Nowitzki's career has wound down and therefore has a fairly limited collection of young talent, adding the 22-year-old Noel without doing any major damage to its rotation counts as a smart play.
周二,萨尔州成为德国第一个禁止外国政客拉票的地区。德国数个地方议会基于消防安全等技术原因,取消了土耳其部长们原计划的拉票集会。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Experts say that 2016 was a remarkable year for the Chinese film industry as it realized growth while facing multiple challenges including the rapid development of the internet, the increasingly sophisticated tastes of Chinese audiences, and the economic downturn in the country.
The unemployment rate probably won't fall quite as rapidly in 2015, according to economists, especially if more people enter the labor force because jobs are easier to find. Yet another large spate of hiring similar to the gain in 2014 would make the low unemployment rate more believable.
Age: 31
5. 持续行动

最近几个月,大宗商品相关行业受到的冲击尤为严重。采矿业全年利润下降23%。石油和石化炼制企业的利润也出现下滑。尽管油价下跌,但很多炼厂仍要接受在油价暴跌之前签订的协议价格,而它们的出厂价格在下跌。

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    Zhu Yongxin, a member of the CPPCC National Committee, full-time vice-chairman of the Central Committee of the China Association for Promoting Democracy and vice-president of the Chinese Society of Education, talking about an NPC deputy representing 670,000 electorates.

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